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Tuvusertib [1613200-51-3]

Tuvusertib [1613200-51-3]

T10406
TargetMol Chemicals
CAS Number1613200-51-3
Product group Chemicals
Estimated Purity99.66%
Molecular Weight370.32
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Tuvusertib
  • Delivery Days Customer
    9
  • CAS Number
    1613200-51-3
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    Tuvusertib
  • Estimated Purity
    99.66%
  • Molecular Formula
    C16H12F2N8O
  • Molecular Weight
    370.32
  • Scientific Description
    Tuvusertib (M1774) is an orally available ataxia telangiectasia and Rad3-related (ATR) kinase inhibitor (Ki< 1 micromicro) with selective and potentially antitumor activity.Tuvusertib selectively inhibits ATR activity and blocks downstream phosphorylation of serine/threonine protein kinase checkpoint kinase 1 (CHK1), thereby inhibits DNA damage checkpoint activation, disrupting DNA damage repair and inducing apoptosis in tumor cells.
  • Shelf life instruction
    3 years
  • SMILES
    Cn1cncc1-c1c(F)cncc1NC(=O)c1c(N)nn2cc(F)cnc12
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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