TVB-3166

MedChem Express

TVB-3166 [1533438-83-3]

10

1533438-83-3

Research Use Only

99.69

C24H24N4O

384.47

TVB-3166 is an orally-available, reversible, and selective fatty acid synthase (FASN) inhibitor with IC 50 s of 42 nM and 81 nM for biochemical FASN and cellular palmitate synthesis, respectively. TVB-3166 induces apoptosis , and inhibits in-vivo xenograft tumor growth [1] .

N#CC1=CC=C(C2CN(C(C3=CC(C4=NNC(C)=C4C)=C(C)C=C3C)=O)C2)C=C1

-20°C,2°C to 8°C

12352200