TX-1918 [503473-32-3]

MedChem Express

TX-1918 [503473-32-3]

5

503473-32-3

Research Use Only

C14H12O3

228.24

TX-1918 is an inhibitor for eukaryotic elongation factor 2 kinase (eEF2-K) and Src kinase with IC50 of 0.44 and 4.4 microM, respectively. TX-1918 exhibits cytotoxicity in cell HepG2 and HCT116, with IC50 of 2.07 and 230 microM, respectively. TX-1918 inhibits the C-terminal domain of HIV-1 CA (CA CTD)(IC50 =3.81 microM), and inhibits the viral replication (IC50 =15.16 microM)[1][2].

O=C1/C(C(C=C1)=O)=C\C2=CC(C)=C(O)C(C)=C2

12352200