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TX1-85-1 [1603845-32-4]

Research Use Only
T17182
TargetMol Chemicals
CAS Number1603845-32-4
Product group Chemicals
Estimated Purity98.12%
Molecular Weight580.68
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    TX1-85-1 [1603845-32-4]
  • Delivery Days Customer
    9
  • CAS Number
    1603845-32-4
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    TX1-85-1
  • Estimated Purity
    98.12%
  • Molecular Formula
    C32H36N8O3
  • Molecular Weight
    580.68
  • Scientific Description
    TX1-85-1 induces partial degradation of Her3 protein and attenuates Her3-dependent signaling. TX1-85-1 is an irreversible Her3 inhibitor (IC50: 23 nM). TX1-85-1 is also the first selective Her3 ligand, which forms a covalent bond with Cys721 located in the ATP-binding site of Her3.
  • Shelf life instruction
    3 years
  • SMILES
    CC(=O)N1CCN(CC1)C1CCC(CC1)n1nc(-c2ccc(Oc3ccccc3)c(NC(=O)C=C)c2)c2c(N)ncnc12
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200