TYK2 JH2-IN-1-d3

MedChem Express

TYK2 JH2-IN-1-d3 [2376999-19-6]

14

Research Use Only

C24H21D3FN9O3

508.52

TYK2 JH2-IN-1-d3 is the a deuterated, orally active and selective TYK2 inhibitor (compound 4h), targeting to JH2 domain (IC50=0.1 nM)[1].

FC1=CN=C(C2=C(OC)C(NC3=C(C(NC([2H])([2H])[2H])=O)N=NC(NC4=NC=C(C(C)(C)O)C=C4)=C3)=NC=C2)N=C1

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