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Tyrphostin AG 879

HY-20878
MedChem Express
CAS Number148741-30-4
Product group Chemicals
Estimated Purity99.85
Molecular Weight316.46
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Tyrphostin AG 879 [148741-30-4]
  • Delivery Days Customer
    10
  • CAS Number
    148741-30-4
  • Certification
    Research Use Only
  • Estimated Purity
    99.85
  • Molecular Formula
    C18H24N2OS
  • Molecular Weight
    316.46
  • Scientific Description
    Tyrphostin AG 879 (AG 879) is a tyrosine kinase inhibitor that inhibits TrKA phosphorylation ( IC 50 of 10 microM), but not TrKB and TrKC. Tyrphostin AG 879 is also a selective ErbB2 tyrosine kinase inhibitor with an IC 50 of 1 microM, and has at least 500-fold higher selectivity to ErbB2 than EGFR. Tyrphostin AG 879 has anticancer activity [1] [2] [3] .
  • SMILES
    S=C(N)/C(C#N)=C/C1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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