U-90042

MedChem Express

U-90042

9

134516-99-7

Research Use Only

C17H13ClN6O

352.78

U-90042 is a gamma-aminobutyric acidA receptor agonist of alpha1, alpha3 and alpha6 subtypes with Ki values of 7.8 nM, 9.5 nM and 11.0 nM, respectively. U-90042 suppresses locomotor activity and impairs rotarod performance in mice. U-90042 produces sedation and ataxia and prolongs sleeping time in mice, rats and monkeys. U-90042 can be used as a sedative and hypnotic agent[1].

ClC1=CC(C2=NCCN2C3=C(C4=NOC(C5CC5)=N4)N=CN63)=C6C=C1

12352200