U0126

MedChem Express

U0126 [109511-58-2]

10

109511-58-2

Research Use Only

98.45

C18H16N6S2

380.49

U0126 is a potent, non-ATP competitive and selective MEK1 and MEK2 inhibitor, with IC50s of 72 nM and 58 nM, respectively. U0126 is an autophagy and mitophagy inhibitor[1][2][3][4].

NC1=CC=CC=C1S/C(N)=C(C#N)/C(C#N)=C(N)/SC2=CC=CC=C2N

-20°C,2°C to 8°C

12352200