UBASH3A Antibody

Cusabio

UBASH3A Antibody

20

ImmunoFluorescence, Western Blot, ELISA

Research Use Only

Polyclonal

Unconjugated

UBASH3A

ubiquitin associated and SH3 domain containing A

CLIP4, STS-2, TULA, TULA-1, ubiquitin-associated and SH3 domain-containing protein A, T-cell ubiquitin ligand 1, T-cell ubiquitin ligand protein, cbl-interacting protein 4, suppressor of T-cell receptor signaling 2

Rabbit

IgG

Ubiquitin-associated and SH3 domain-containing protein A

Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors, EGFR and PDGFRB, on the cell surface. Exhibits negligigle protein tyrosine phosphatase activity at neutral pH. May act as a dominant-negative regulator of UBASH3B-dependent dephosphorylation. May inhibit dynamin-dependent endocytic pathways by functionally sequestering dynamin via its SH3 domain.

Human

-20°C or -80°C

41116161