UBASH3B Antibody

Cusabio

UBASH3B Antibody

20

ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

UBASH3B

ubiquitin associated and SH3 domain containing B

STS-1, STS1, TULA-2, TULA2, p70, ubiquitin-associated and SH3 domain-containing protein B, Cbl-interacting protein Sts-1, SH3 domain-containing 70 kDa protein, suppressor of T-cell receptor signaling 1, nm23-phosphorylated unknown substrate, T-cell ubiquitin ligand 2, cbl-interacting protein p70, nm23-phosphorylated unknown substrate, suppressor of T-cell receptor signaling 1, tyrosine-protein phosphatase STS1/TULA2

Rabbit

IgG

Ubiquitin-associated and SH3 domain-containing protein B

Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors and EGFR, on the cell surface. Exhibits tyrosine phosphatase activity toward several substrates including EGFR, FAK, SYK, and ZAP70. Down-regulates proteins that are dually modified by both protein tyrosine phosphorylation and ubiquitination.

Human

-20°C or -80°C

41116161