UBASH3B Antibody

Cusabio

UBASH3B Antibody

20

ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

UBASH3B

ubiquitin associated and SH3 domain containing B

cbl-interacting protein p70; Cbl-interacting protein Sts-1; nm23-phosphorylated unknown substrate; p70; SH3 domain-containing 70 kDa protein, suppressor of T-cell receptor signaling 1, nm23-phosphorylated unknown substrate; STS1; STS-1; suppressor of T-cell receptor signaling 1; T-cell ubiquitin ligand 2; TULA2; TULA-2; tyrosine-protein phosphatase STS1/TULA2; ubiquitin-associated and SH3 domain-containing protein B

Rabbit

IgG

Ubiquitin-associated and SH3 domain-containing protein B

Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors and EGFR, on the cell surface. Exhibits tyrosine phosphatase activity toward several substrates including EGFR, FAK, SYK, and ZAP70. Down-regulates proteins that are dually modified by both protein tyrosine phosphorylation and ubiquitination.

Human

-20°C or -80°C

41116161