UBASH3B/STS1, Human (His)

MedChem Express

UBASH3B/STS1, Human (His)

10

Research Use Only

95.0

UBASH3B

ubiquitin associated and SH3 domain containing B

cbl-interacting protein p70; Cbl-interacting protein Sts-1; nm23-phosphorylated unknown substrate; p70; SH3 domain-containing 70 kDa protein, suppressor of T-cell receptor signaling 1, nm23-phosphorylated unknown substrate; STS1; STS-1; suppressor of T-cell receptor signaling 1; T-cell ubiquitin ligand 2; TULA2; TULA-2; tyrosine-protein phosphatase STS1/TULA2; ubiquitin-associated and SH3 domain-containing protein B

Ubiquitin-associated and SH3 domain-containing protein B

UBASH3B/STS1 protein blocks CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases, leading to the accumulation of activating receptors such as T cell receptors and EGFR on the cell surface. It exhibits tyrosine phosphatase activity against substrates such as EGFR, FAK, SYK and ZAP70. UBASH3B/STS1 Protein, Human (His) is the recombinant human-derived UBASH3B/STS1 protein, expressed by E. coli , with N-His labeled tag.

-20°C

41116100