UBASH3B/STS1, Human (His)

MedChem Express

UBASH3B/STS1, Human (His)

10

Research Use Only

95.0

UBASH3B

ubiquitin associated and SH3 domain containing B

STS-1, STS1, TULA-2, TULA2, p70, ubiquitin-associated and SH3 domain-containing protein B, Cbl-interacting protein Sts-1, SH3 domain-containing 70 kDa protein, suppressor of T-cell receptor signaling 1, nm23-phosphorylated unknown substrate, T-cell ubiquitin ligand 2, cbl-interacting protein p70, nm23-phosphorylated unknown substrate, suppressor of T-cell receptor signaling 1, tyrosine-protein phosphatase STS1/TULA2

Ubiquitin-associated and SH3 domain-containing protein B

UBASH3B/STS1 protein blocks CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases, leading to the accumulation of activating receptors such as T cell receptors and EGFR on the cell surface. It exhibits tyrosine phosphatase activity against substrates such as EGFR, FAK, SYK and ZAP70. UBASH3B/STS1 Protein, Human (His) is the recombinant human-derived UBASH3B/STS1 protein, expressed by E. coli , with N-His labeled tag.

-20°C

41116100