UbcH5c-IN-1

MedChem Express

UbcH5c-IN-1 [2123480-72-6]

10

2123480-72-6

Research Use Only

99.84

C22H21BrO3

413.30

UbcH5c-IN-1 (compound 6d) is a potent and selective small-molecule inhibitor of Ubiquitin-conjugating enzyme UbcH5c , with a K d of 283 nM for E2 UbcH5c-IN-1 by covalent binding with Cys85. A promising lead compound for the development of new antirheumatoid arthritis (RA) agent [1] .

BrC1=CC=CC=C1COC2=C(C)C([C@H](OC(C3=C)=O)[C@H]3CC4)=C4C(C)=C2

-20°C,2°C to 8°C

12352200