UBE1L antibody [5B10]

GeneTex

UBE1L antibody [5B10]

9

WB: 1/500 - 1/2000. ELISA: 1/10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ELISA

Research Use Only

Monoclonal

5B10

Unconjugated

UBA7

ubiquitin like modifier activating enzyme 7

D8, UBA1B, UBE1L, UBE2, UBE7, ubiquitin-like modifier-activating enzyme 7, UBA1, ubiquitin-activating enzyme E1 homolog B, UBA7, ubiquitin-activating enzyme E1, ubiquitin-activating enzyme 7, ubiquitin-activating enzyme E1 homolog, ubiquitin-activating enzyme E1-related protein, ubiquitin-activating enzyme-2

Mouse

IgG1

Ubiquitin-like modifier-activating enzyme 7

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein. [provided by RefSeq, Jul 2008]

Human

-20°C or -80°C,2°C to 8°C

12352203