UBE4B antibody [C2C3], C-term

GeneTex

UBE4B antibody [C2C3], C-term

9

WB: 1:5000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

UBE4B

ubiquitination factor E4B

E4; HDNB1; homologous to yeast UFD2; homozygously deleted in neuroblastoma-1; RING-type E3 ubiquitin transferase E4 B; ubiquitin conjugation factor E4 B; ubiquitination factor E4B (UFD2 homolog, yeast); ubiquitin-fusion degradation protein 2; UBOX3; UFD2; UFD2A

Rabbit

IgG

Ubiquitin conjugation factor E4 B

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq]

Human

-20°C or -80°C,2°C to 8°C

12352203