Ubiquilin 1 antibody [N1C1]
![Research Use Only](static/images/certificates/ruo.jpg)
GTX111485
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman
TargetUBQLN1
Overview
- SupplierGeneTex
- Product NameUbiquilin 1 antibody [N1C1]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID29979
- Target nameUBQLN1
- Target descriptionubiquilin 1
- Target synonymsDA41; DSK2; hPLIC-1; PLIC-1; protein linking IAP with cytoskeleton 1; testicular tissue protein Li 219; ubiquilin-1; UBQN; XDRP1
- HostRabbit
- IsotypeIgG
- Protein IDQ9UMX0
- Protein NameUbiquilin-1
- Scientific DescriptionThis gene encodes an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimers and Parkinsons disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Inhibitory effect of chloroquine derivatives on presenilin 1 and ubiquilin 1 expression in Alzheimers disease. Zhang FF et al., 2015, Int J Clin Exp PatholRead more