Bio-Connect

UC2288

M11331
AbMole BioScience
CAS Number1394011-91-6
Product group Chemicals
Molecular Weight481.82
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    UC2288
  • Delivery Days Customer
    9
  • CAS Number
    1394011-91-6
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Molecular Formula
    C20H18ClF6N3O2
  • Molecular Weight
    481.82
  • Scientific Description
    UC2288 is a novel p21 attenuator with cellular permeability and oral activity (relatively selective activity for P21), based on the structural synthesis of sorafenib. UC2288 down-regulated the expression of P21 mRNA and reduced the level of P21 protein independently of p53, and had little effect on the stability of P21 protein. UC2288 did not inhibit VEGFR2 and Raf kinases, even at 10 uM.
  • SMILES
    FC(F)(F)C1=CC=C(OC2CCC(CC2)NC(=O)NC3=CC(=C(Cl)C=C3)C(F)(F)F)N=C1
  • UNSPSC
    12352200

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UC2288 [1394011-91-6]
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