UCB-9260 [1515888-53-5]

MedChem Express

UCB-9260 [1515888-53-5]

10

1515888-53-5

Research Use Only

98.38

C26H25N5O

423.51

UCB-9260, an orally active compound, inhibits TNF signaling by stabilising an asymmetric form of the trimer. UCB-9260 is selective for TNF over other superfamily members, and binds TNF with a similar Kd of 13 nM[1].

OC(C1=CC=NC=C1)C2=NC3=CC=C(C4=CN(C)N=C4)C=C3N2CC5=CC(C)=CC=C5C

-20°C

12352200