UCP3 antibody

GeneTex

UCP3 antibody

9

WB: 1:1,000. IHC-P: 1:3,000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

Unconjugated

UCP3

uncoupling protein 3

mitochondrial uncoupling protein 3; SLC25A9; solute carrier family 25 member 9; uncoupling protein 3 (mitochondrial, proton carrier)

Rabbit

IgG

Mitochondrial uncoupling protein 3

The uncoupling proteins (UCPs) are found in the inner mitochondrial membranes and belong to a family of mitochondrial anion transport proteins that include the phosphate and oxologutarate carriers and the ADP/ATP translocator. Three UCP subtypes have been identified and cloned. UCP 1 is abundantly expressed in brown adipose tissue of mammals. UCP 1 allows proton re-entry into the mitochondrial matrix without involving the F0-F1 ATPase which produces heat instead of ATP. It is thought that UCP 2 and 3 also dissipate the mitochondrial proton gradient produced by the respiratory chain in cells and tissues within which they are expressed. Studies have shown UCP 2 to be expressed by a variety of tissues. UCP 3 is expressed predominantly in brown adipose tissue, skeletal muscle, at lower levels in heart and smooth muscle, and is absent in liver and kidney.

Human, Mouse, Rat

-20°C or -80°C,2°C to 8°C

12352203