UFD1L Polyclonal Antibody
RD82887A
ApplicationsImmunoFluorescence, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetUFD1
Overview
- SupplierReddot Biotech
- Product NameUFD1L Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsImmunoFluorescence, ImmunoHistoChemistry
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID7353
- Target nameUFD1
- Target descriptionubiquitin recognition factor in ER associated degradation 1
- Target synonymsUB fusion protein 1; ubiquitin fusion degradation 1 like; ubiquitin fusion degradation protein 1 homolog; ubiquitin recognition factor in ER-associated degradation protein 1; UFD1L
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18.
- ReactivityHuman, Mouse
- Storage Instruction-20°C
- UNSPSC12352203