Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA025560LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA025560LA01HU at dilution of 1:100
UFM1 Antibody
CSB-PA025560LA01HU
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetUFM1
Overview
- SupplierCusabio
- Product NameUFM1 Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID51569
- Target nameUFM1
- Target descriptionubiquitin fold modifier 1
- Target synonymsBM-002; C13orf20; HLD14; ubiquitin-fold modifier 1
- HostRabbit
- IsotypeIgG
- Protein IDP61960
- Protein NameUbiquitin-fold modifier 1
- Scientific DescriptionUbiquitin-like modifier which can be covalently attached via an isopeptide bond to substrate proteins as a monomer or a lysine-linked polymer. The so-called ufmylation, requires the UFM1-activating E1 enzyme UBA5, the UFM1-conjugating E2 enzyme UFC1, and the UFM1-ligase E3 enzyme UFL1 (PubMed:15071506, PubMed:20018847). This post-translational modification on lysine residues of proteins may play a crucial role in a number of cellular processes. TRIP4 ufmylation may for instance play a role in nuclear receptors-mediated transcription (PubMed:25219498). Other substrates may include DDRGK1 with which it may play a role in the cellular response to endoplasmic reticulum stress (Probable).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203