ULK2 antibody [C2C3], C-term
![Research Use Only](static/images/certificates/ruo.jpg)
GTX111476
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetULK2
Overview
- SupplierGeneTex
- Product NameULK2 antibody [C2C3], C-term
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.24 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID9706
- Target nameULK2
- Target descriptionunc-51 like autophagy activating kinase 2
- Target synonymsATG1B; serine/threonine-protein kinase ULK2; Unc51.2
- HostRabbit
- IsotypeIgG
- Protein IDQ8IYT8
- Protein NameSerine/threonine-protein kinase ULK2
- Scientific DescriptionThis gene encodes a protein that is similar to a serine/threonine kinase in C. elegans which is involved in axonal elongation. The structure of this protein is similar to the C. elegans protein in that both proteins have an N-terminal kinase domain, a central proline/serine rich (PS) domain, and a C-terminal (C) domain. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Metabolic regulation of RA macrophages is distinct from RA fibroblasts and blockade of glycolysis alleviates inflammatory phenotype in both cell types. Umar S et al., 2021 Dec, Cell Mol Life SciRead more
- Coxsackievirus infection induces a non-canonical autophagy independent of the ULK and PI3K complexes. Mohamud Y et al., 2020 Nov 4, Sci RepRead more
- TBC1D9 regulates TBK1 activation through Ca2+ signaling in selective autophagy. Nozawa T et al., 2020 Feb 7, Nat CommunRead more
- Overexpression of Ulk2 inhibits proliferation and enhances chemosensitivity to cisplatin in non-small cell lung cancer. Cheng H et al., 2019 Jan, Oncol LettRead more
- RAB7A phosphorylation by TBK1 promotes mitophagy via the PINK-PARKIN pathway. Heo JM et al., 2018 Nov, Sci AdvRead more