Umibecestat [1387560-01-1]

TargetMol Chemicals

Umibecestat [1387560-01-1]

9

1387560-01-1

Chemical

Research Use Only

Umibecestat

C19H15ClF7N5O2

513.8

Umibecestat is an inhibitor of beta-site amyloid precursor protein cleaving enzyme-1 (BACE-1), with IC50s of 11 nM and 10 nM for human BACE-1 and mouse BACE-1, respectively. Umibecestat can be used for the research of alzheimers disease.

3 years

C[C@]1(CO[C@](C)(C(N)=N1)C(F)(F)F)c1nc(NC(=O)c2ncc(cc2Cl)C(F)(F)F)ccc1F

-20°C

12352200