Bio-Connect

UMPS Polyclonal Antibody

Research Use Only
RD83342A
Reddot Biotech
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetUMPS
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    UMPS Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID7372
  • Target name
    UMPS
  • Target description
    uridine monophosphate synthetase
  • Target synonyms
    OMPdecase; OPRT; OPRTase; orotate phosphoribosyltransferase; orotidine 5'-phosphate decarboxylase; UMP synthase; uridine 5'-monophosphate synthase
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a uridine 5-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203