UMPS Polyclonal Antibody

Reddot Biotech

UMPS Polyclonal Antibody

5

1 mg/ml

UMPS

uridine monophosphate synthetase

OMPdecase; OPRT; OPRTase; orotate phosphoribosyltransferase; orotidine 5'-phosphate decarboxylase; UMP synthase; uridine 5'-monophosphate synthase

This gene encodes a uridine 5-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.

-20°C

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