UNC-2170 [1648707-58-7]

MedChem Express

UNC-2170 [1648707-58-7]

10

1648707-58-7

Research Use Only

98.84

C14H21BrN2O

313.23

UNC-2170 is a functionally active, fragment-like ligand for 53BP1 (IC50=29 microM; Kd=22 microM). UNC-2170 shows at least 17-fold selectivity for 53BP1 as compared to nine other methyl-lysine (Kme) reader proteins. 53BP1 is a Kme binding protein that plays a central role in DNA Damage Repair (DDR) pathways and is recruited to sites of double-strand breaks (DSB)[1].

O=C(NCCCNC(C)(C)C)C1=CC=CC(Br)=C1

2°C to 8°C

12352200