Overview
- SupplierTargetMol Chemicals
- Product NameUNC 569 hydrochloride
- Delivery Days Customer9
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameUNC 569 hydrochloride
- Molecular FormulaC22H30ClFN6
- Molecular Weight432.96
- Scientific DescriptionUNC 569 hydrochloride is a reversible and ATP-competitive inhibitor of Mer with an IC50 of 2.9 nM and a Ki of 4.3 nM. UNC 569 hydrochloride inhibits Axl and Tyro3 with IC50s of 37 nM and 48 nM, respectively. UNC 569 hydrochloride can be used in studies about acute lymphoblastic leukemia and atypical teratoid/rhabdoid tumors.
- Shelf life instruction3 years
- SMILESCCCCNC1=NC=C(C2=N1)C(C3=CC=C(F)C=C3)=NN2C[C@@H]4CC[C@@H](N)CC4.Cl
- Storage Instruction-20°C
- UNSPSC12352200
References
- UNC569, a novel small-molecule mer inhibitor with efficacy against acute lymphoblastic leukemia in vitro and in vivo. Christoph S et al., 2013 Nov, Mol Cancer TherRead more