UNC119 antibody [N2C3]
GTX115185
Overview
- SupplierGeneTex
- Product NameUNC119 antibody [N2C3]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID9094
- Target nameUNC119
- Target descriptionunc-119 lipid binding chaperone
- Target synonymsHRG4; IMD13; POC7; POC7 centriolar protein homolog A; POC7A; protein unc-119 homolog A; retinal protein 4; unc-119 homolog
- HostRabbit
- IsotypeIgG
- Protein IDQ13432
- Protein NameProtein unc-119 homolog A
- Scientific DescriptionThis gene is specifically expressed in the photoreceptors in the retina. The encoded product shares strong homology with the C. elegans unc119 protein and it can functionally complement the C. elegans unc119 mutation. It has been localized to the photoreceptor synapses in the outer plexiform layer of the retina, and suggested to play a role in the mechanism of photoreceptor neurotransmitter release through the synaptic vesicle cycle. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Spatial cycles mediated by UNC119 solubilisation maintain Src family kinases plasma membrane localisation. Konitsiotis AD et al., 2017 Jul 24, Nat CommunRead more
- Highly expressed UNC119 promotes hepatocellular carcinoma cell proliferation through Wnt/beta-catenin signaling and predicts a poor prognosis. Lei B et al., 2015, Am J Cancer ResRead more