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GTX115185 WB Image
GTX115185 WB Image
GTX115185 WB Image

UNC119 antibody [N2C3]

Research Use Only
GTX115185
GeneTex
Product group Antibodies
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    UNC119 antibody [N2C3]
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Isotype
    IgG
  • Scientific Description
    This gene is specifically expressed in the photoreceptors in the retina. The encoded product shares strong homology with the C. elegans unc119 protein and it can functionally complement the C. elegans unc119 mutation. It has been localized to the photoreceptor synapses in the outer plexiform layer of the retina, and suggested to play a role in the mechanism of photoreceptor neurotransmitter release through the synaptic vesicle cycle. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Highly expressed UNC119 promotes hepatocellular carcinoma cell proliferation through Wnt/beta-catenin signaling and predicts a poor prognosis. Lei B et al., 2015, Am J Cancer Res
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  • Spatial cycles mediated by UNC119 solubilisation maintain Src family kinases plasma membrane localisation. Konitsiotis AD et al., 2017 Jul 24, Nat Commun
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