UNC569

MedChem Express

UNC569 [1350547-65-7]

10

1350547-65-7

Research Use Only

99.87

C22H29FN6

396.50

UNC569 is a potent, reversible, ATP-competitive and orally active Mer kinase inhibitor with an IC 50 of 2.9 nM and a K i of 4.3 nM. UNC569 also inhibits Axl and Tyro3 with IC 50 s of 37 nM and 48 nM, respectively. UNC569 can be used for acute lymphoblastic leukemia (ALL) and atypical teratoid/rhabdoid tumors research [1] [2]

FC1=CC=C(C2=NN(C[C@H]3CC[C@H](N)CC3)C4=NC(NCCCC)=NC=C42)C=C1

-20°C,2°C to 8°C

12352200