UNC6934

Biorbyt

UNC6934 [2561494-77-5]

10

2561494-77-5

Research Use Only

C24H21N5O4

443.16

UNC6934 is a potent and selective drug-like chemical probe to interrogate the function of NSD2-PWWP1 with Kd of 91 nM.UNC6934 disrupts the NSD2-PWWP1 interaction with H3K36me2 nucleosomes in U2OS cells as measured by a NanoBret assay with an IC50 of 1.09

O=C(NC=1N=CN=CC1)C2=CC=C(C=C2)CN(C(=O)C3=CC=C4NC(=O)COC4=C3)C5CC5

12352200