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Upadacitinib

M6297
AbMole BioScience
CAS Number1310726-60-3
Product group Chemicals
Molecular Weight380.37
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    Upadacitinib
  • Delivery Days Customer
    9
  • CAS Number
    1310726-60-3
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Molecular Formula
    C17H19F3N6O
  • Molecular Weight
    380.37
  • Scientific Description
    Upadacitinib (ABT-494) is a potent, orally active and selective Janus kinase 1 (JAK1) inhibitor (IC50=43 nM). Upadacitinib (ABT-494) displays approximately 74 fold selective for JAK1 over JAK2 (200 nM) in cellular assays dependent on specific, relevant cytokines. Upadacitinib (ABT-494) can be used for several autoimmune disorders research.
  • SMILES
    CCC1CN(CC1C2=CN=C3C=NC4=C(C=C[NH]4)[N]23)C(=O)NCC(F)(F)F
  • UNSPSC
    12352200