UPCDC-30245 [1883351-01-6]

MedChem Express

UPCDC-30245 [1883351-01-6]

5

1883351-01-6

Research Use Only

99.85

C28H38FN5

463.63

UPCDC-30245 is an allosteric p97 inhibitor with an IC50 of approximately 27 nM[1]. UPCDC-30245 inhibits the p97 mutant N660K similar to wild type (WT; IC50=300 nM) and shows 3-fold resistance for p97 mutant T688A[2]. UPCDC-30245 can be used in the research of cancer[1][2][3].

CC(N1CCN(CCNC2CCN(C3=CC=CC(C(N4)=CC5=C4C=CC(F)=C5)=C3)CC2)CC1)C

-20°C,2°C to 8°C

12352200