UPF-523

MedChem Express

UPF-523 [168560-79-0]

5

168560-79-0

99.89

C11H11NO4

221.21

UPF-523 (AIDA), a rigid (carboxyphenyl) glycine derivative, is a relatively potent and selective antagonist of group I metabotropic glutamate receptors (mGlu1a) with an IC 50 of 214 microM. But UPF-523 has no effect on group II (mGlu2), group III (mGlu4) receptors or ionotropic glutamate receptors. UPF-523 has the potential for the research of the acute arthritis [1] [2] .

O=C(C1(N)CCC2=C1C=CC(C(O)=O)=C2)O

-20°C,2°C to 8°C

12352200