Upidosin [152735-23-4]

MedChem Express

Upidosin [152735-23-4]

10

152735-23-4

Research Use Only

99.48

C31H33N3O4

511.61

Upidosin (Rec 15/2739) is an alpha-1 adrenoceptor (alpha-1 AR) antagonist. Upidosin shows moderate selectivity for the alpha-1A AR subtype. Upidosin shows uroselectivity in urethra and prostate with a Kb value of 2-3 nM higher than in ear artery and aorta with a Kb value of 20-100 nM. Upidosin inhibits [3H]prazosin binding to cloned human alpha-1A adrenergic receptor. Upidosin can be used for the research of urethral obstruction[1].

COC(C=CC=C1)=C1N(CC2)CCN2CCCNC(C3=C4C(C(C(C)=C(C5=CC=CC=C5)O4)=O)=CC=C3)=O

2°C to 8°C

12352200