UPK1A antibody [MSVA-735M] HistoMAX(tm)

GeneTex

UPK1A antibody [MSVA-735M] HistoMAX(tm)

9

IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

MSVA-735M

0.2 mg/ml

Unconjugated

UPK1A

uroplakin 1A

tetraspanin-21; TSPAN21; tspan-21; UP1A; UPIA; UPKA; uroplakin Ia; uroplakin-1a

Mouse

IgG2b

Uroplakin-1a

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The protein may also play a role in tumor suppression. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]

-20°C or -80°C,2°C to 8°C

12352203