Uprosertib [1047634-65-0]

AbMole BioScience

Uprosertib [1047634-65-0]

7

1047634-65-0

Research Use Only

98.21%

C18H16Cl2F2N4O2

429.25

Uprosertib (GSK2141795) is a potent and selective pan-Akt inhibitor with IC50 values of 180 nM for Akt1, 328 nM for Akt2, and 38 nM for Akt3 respectively (Clinical phase 1).

C[N]1N=CC(=C1C2=C(Cl)OC(=C2)C(=O)NC(CN)CC3=CC(=C(F)C=C3)F)Cl

-20°C, sealed

12161500