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ProductsBack/UQCRC2 antibody

UQCRC2 antibody

GTX114873
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, Other Application
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetUQCRC2
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Overview

  • Supplier
    GeneTex
  • Product Name
    UQCRC2 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:5000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, Other Application
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.37 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID7385
  • Target name
    UQCRC2
  • Target description
    ubiquinol-cytochrome c reductase core protein 2
  • Target synonyms
    complex III subunit 2; cytochrome bc-1 complex core protein II; cytochrome b-c1 complex subunit 2, mitochondrial; MC3DN5; QCR2; ubiquinol-cytochrome c reductase core protein II; ubiquinol-cytochrome-c reductase complex core protein 2; UQCR2
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP22695
  • Protein Name
    Cytochrome b-c1 complex subunit 2, mitochondrial
  • Scientific Description
    This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. The core protein 2 is required for the assembly of the complex.
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • The mitochondrial fusion protein OPA1 is dispensable in the liver and its absence induces mitohormesis to protect liver from drug-induced injury.
    Read more
  • Cytosolic and mitochondrial translation elongation are coordinated through the molecular chaperone TRAP1 for the synthesis and import of mitochondrial proteins.
    Read more
  • Regulation of mitochondrial complex III activity and assembly by TRAP1 in cancer cells.
    Read more
  • Gut microbiota production of trimethyl-5-aminovaleric acid reduces fatty acid oxidation and accelerates cardiac hypertrophy. Zhao M et al., 2022 Apr 1, Nat Commun
    Read more
  • The short variant of optic atrophy 1 (OPA1) improves cell survival under oxidative stress. Lee H et al., 2020 May 8, J Biol Chem
    Read more
  • Phosphorylation of the Ribosomal Protein RPL12/uL11 Affects Translation during Mitosis. Imami K et al., 2018 Oct 4, Mol Cell
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  • Optic atrophy 1 mediates coenzyme Q-responsive regulation of respiratory complex IV activity in brain mitochondria. Takahashi K et al., 2017 Nov, Exp Gerontol
    Read more
  • The short variant of the mitochondrial dynamin OPA1 maintains mitochondrial energetics and cristae structure. Lee H et al., 2017 Apr 28, J Biol Chem
    Read more