Uridine 5-diphosphoglucose [133-89-1]

MedChem Express

Uridine 5-diphosphoglucose [133-89-1]

10

133-89-1

Research Use Only

C15H24N2O17P2

566.30

Uridine 5-diphosphoglucose (UDP-glucose), secreted by cardiomyocytes during ischemia and reperfu, is a potent agonist of the proinflammatory P2Y14 receptor. It acts an important role in the regulation of inflammation and neutrophil polarization in neutrophils. Uridine 5-diphosphoglucose is also the precursor of glucose-containing oligosaccharides, polysaccharides, glycoproteins, and glycolipids in animal tissues and in some microorganisms. Uridine 5-diphosphoglucose is promising for research in counteracting myocardial infarction/reperfusion (MIR)-induced inflammation in the heart tissue[1][2][3][4].

O[C@@H]1[C@H](O)[C@@H](COP(O)(OP(O)(O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)=O)=O)O[C@H]1N3C=CC(NC3=O)=O

12352200