Uroplakin 1B (Urothelial Differentiation Marker)(UPK1B/3273), CF740 conjugate, 0.1mg/mL

Biotium

Uroplakin 1B (Urothelial Differentiation Marker)(UPK1B/3273), CF740 conjugate, 0.1mg/mL

16

ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

UPK1B/3273

0.1 mg/ml

Other Conjugate

UPK1B

uroplakin 1B

TSPAN20, UPIB, UPK1, uroplakin-1b, UP1b, tetraspan, tetraspanin-20, tspan-20, uroplakin Ib

IgG1

Uroplakin-1b

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. UPK1B is expressed by terminally differentiated urothelial cells. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Animal

2°C to 8°C,RT

41116100