
Western blot All lanes: USP14 antibody at 2microg/ml Lane 1: Hela whole cell lysate Lane 2: 293T whole cell lysate Lane 3: NIH/3T3 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 57, 53, 55 kDa Observed band size: 57 kDa
USP14 Antibody
CSB-PA025704LA01HU
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
TargetUSP14
Overview
- SupplierCusabio
- Product NameUSP14 Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID9097
- Target nameUSP14
- Target descriptionubiquitin specific peptidase 14
- Target synonymsdeubiquitinating enzyme 14; TGT; tRNA-guanine transglycosylase, 60-kD subunit; ubiquitin carboxyl-terminal hydrolase 14; ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase); ubiquitin specific protease 14 (tRNA-guanine transglycosylase); ubiquitin thioesterase 14; ubiquitin thiolesterase 14; ubiquitin-specific processing protease 14
- HostRabbit
- IsotypeIgG
- Protein IDP54578
- Protein NameUbiquitin carboxyl-terminal hydrolase 14
- Scientific DescriptionProteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions (NMJs).
- Storage Instruction-20°C or -80°C
- UNSPSC12352203