Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using USP2 Polyclonal Antibody at dilution 1:40
Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using USP2 Polyclonal Antibody at dilution 1:40
USP2 Polyclonal Antibody
E-AB-10878
Product group Antibodies
Overview
- SupplierElabscience
- Product NameUSP2 Polyclonal Antibody
- Delivery Days Customer12
- Applications SupplierELISA IHC
- CertificationResearch Use Only
- Concentration0.3mg/ml
- Scientific DescriptionThis gene encodes a member of the family of de-ubiquitinating enzymes, which belongs to the peptidase C19 superfamily. The encoded protein is a ubiquitin-specific protease which is required for TNF-alpha (tumor necrosis factor alpha) -induced NF-kB (nuclear factor kB) signaling. This protein deubiquitinates polyubiquitinated target proteins such as fatty acid synthase, murine double minute 2 (MDM2), MDM4/MDMX and cyclin D1. MDM2 and MDM4 are negative regulators of the p53 tumor suppressor and cyclin D1 is required for cell cycle G1/S transition. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
- UNSPSC12352203