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USP22 antibody [N3C3]

GTX120048
GeneTex
ApplicationsImmunoPrecipitation, Western Blot
Product group Antibodies
ReactivityHuman
TargetUSP22
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Overview

  • Supplier
    GeneTex
  • Product Name
    USP22 antibody [N3C3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoPrecipitation, Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID23326
  • Target name
    USP22
  • Target description
    ubiquitin specific peptidase 22
  • Target synonyms
    deubiquitinating enzyme 22; ubiquitin carboxyl-terminal hydrolase 22; ubiquitin specific protease 22; ubiquitin thioesterase 22; ubiquitin thiolesterase 22; ubiquitin-specific processing protease 22; USP3L
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9UPT9
  • Protein Name
    Ubiquitin carboxyl-terminal hydrolase 22
  • Scientific Description
    Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression.
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Epigenetic regulation of ferroptosis by H2B monoubiquitination and p53. Wang Y et al., 2019 Jul, EMBO Rep
    Read more
  • Histone H2B monoubiquitination is a critical epigenetic switch for the regulation of autophagy. Chen S et al., 2017 Feb 17, Nucleic Acids Res
    Read more