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GTX120048 IP Image
GTX120048 IP Image
GTX120048 IP Image

USP22 antibody [N3C3]

Research Use Only
GTX120048
GeneTex
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Product group Antibodies
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More than 130 suppliers
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Overview

  • Supplier
    GeneTex
  • Product Name
    USP22 antibody [N3C3]
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Isotype
    IgG
  • Scientific Description
    Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression.
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Epigenetic regulation of ferroptosis by H2B monoubiquitination and p53. Wang Y et al., 2019 Jul, EMBO Rep
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  • Histone H2B monoubiquitination is a critical epigenetic switch for the regulation of autophagy. Chen S et al., 2017 Feb 17, Nucleic Acids Res
    Read more