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USP25/28 inhibitor AZ1 [2165322-94-9]

USP25/28 inhibitor AZ1 [2165322-94-9]

T7685
TargetMol Chemicals
CAS Number2165322-94-9
Product group Chemicals
Estimated Purity99.79%
Molecular Weight422.21
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    USP25/28 inhibitor AZ1 [2165322-94-9]
  • Delivery Days Customer
    4
  • CAS Number
    2165322-94-9
  • Certification
    Research Use Only
  • Chemical Name
    USP25/28 inhibitor AZ1
  • Estimated Purity
    99.79%
  • Molecular Formula
    C17H16BrF4NO2
  • Molecular Weight
    422.21
  • Scientific Description
    USP25/28 inhibitor AZ1 is a selective, orally active and non-competitive dual ubiquitin-specific protease USP25/28 inhibitor with IC50 of 0.7 microM and 0.6 microM, respectively, and exhibits anti-inflammatory and anti-tumor effects.
  • Shelf life instruction
    3 years
  • SMILES
    OCCNCc1cc(Br)ccc1OCc1ccc(F)c(c1)C(F)(F)F
  • Storage Instruction
    -20°C
  • UNSPSC
    51202000

References

  • Wang XM, Yang C, Zhao Y, et al. The deubiquitinase USP25 supports colonic inflammation and bacterial infection and promotes colorectal cancer. Nat Cancer. 2020,1(8):811-825. doi: 10.1038/s43018-020-0089-4
    Read this paper

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