Bio-Connect

USP28-IN-2 [2931509-11-2]

T74792
TargetMol Chemicals
Molecular Weight475.39
Product group Chemicals
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    USP28-IN-2 [2931509-11-2]
  • Delivery Days Customer
    72
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    USP28-IN-2
  • Molecular Formula
    C23H20Cl2N2O3S
  • Molecular Weight
    475.39
  • Scientific Description
    USP28-IN-2 is a selective USP28 inhibitor (IC50 = 0.3 microM), demonstrating high specificity compared to USP2, USP7, USP8, USP9x, UCHL3, and UCHL5. This compound exhibits cytotoxic effects on cancer cells and induces the degradation of c-Myc via the ubiquitin-proteasome pathway. Additionally, USP28-IN-2 reduces ankyrin-1/2 levels in vitro and potentiates the responsiveness of colorectal cancer cells to Regorafenib [1].
  • Shelf life instruction
    3 years
  • Storage Instruction
    -20°C
  • UNSPSC
    51202000