USP28-IN-4 [2931509-15-6]

TargetMol Chemicals

USP28-IN-4 [2931509-15-6]

10

Chemical

Research Use Only

USP28-IN-4

98.48%

C22H18Cl2N2O3S

461.36

USP28-IN-4 is a potent USP28 inhibitor with an IC50 value of 0.04 microM against USP28. USP28-IN-4 exhibits anticancer activity and inhibits USP2, USP7, USP8, USP9x, UCHL3 and UCHL5. USP28-IN-4 is cytotoxic to human colorectal and lung squamous carcinoma cells and dose-dependently downregulates c-Myc cellular levels through the ubiquitin-proteasome system. -proteasome system to dose-dependently downregulate cellular levels of c-Myc.

3 years

O=C(NC1=CC=C(Cl)C(=C1)C=2C=CC3=C(C2)CNC3)C4=CC=C(C=C4Cl)S(=O)(=O)C

-20°C

51202000