USP46 antibody
GTX117994
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetUSP46
Overview
- SupplierGeneTex
- Product NameUSP46 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.96 mg/ml
- ConjugateUnconjugated
- Gene ID64854
- Target nameUSP46
- Target descriptionubiquitin specific peptidase 46
- Target synonymsubiquitin carboxyl-terminal hydrolase 46, deubiquitinating enzyme 46, ubiquitin thioesterase 46, ubiquitin thiolesterase 46, ubiquitin-specific-processing protease 46
- HostRabbit
- IsotypeIgG
- Protein IDP62068
- Protein NameUbiquitin carboxyl-terminal hydrolase 46
- Scientific DescriptionModification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP46 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).[supplied by OMIM]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Wang Y, Yang L, Zhang X, et al. Epigenetic regulation of ferroptosis by H2B monoubiquitination and p53. EMBO Rep. 2019,20(7):e47563. doi: 10.15252/embr.201847563Read this paper
- Chen S, Jing Y, Kang X, et al. Histone H2B monoubiquitination is a critical epigenetic switch for the regulation of autophagy. Nucleic Acids Res. 2017,45(3):1144-1158. doi: 10.1093/nar/gkw1025



