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USP46 antibody

GTX117994
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetUSP46
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Overview

  • Supplier
    GeneTex
  • Product Name
    USP46 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.96 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID64854
  • Target name
    USP46
  • Target description
    ubiquitin specific peptidase 46
  • Target synonyms
    deubiquitinating enzyme 46; ubiquitin carboxyl-terminal hydrolase 46; ubiquitin thioesterase 46; ubiquitin thiolesterase 46; ubiquitin-specific-processing protease 46
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP62068
  • Protein Name
    Ubiquitin carboxyl-terminal hydrolase 46
  • Scientific Description
    Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP46 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).[supplied by OMIM]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Epigenetic regulation of ferroptosis by H2B monoubiquitination and p53. Wang Y et al., 2019 Jul, EMBO Rep
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  • Histone H2B monoubiquitination is a critical epigenetic switch for the regulation of autophagy. Chen S et al., 2017 Feb 17, Nucleic Acids Res
    Read more