Western blot All lanes: USP5 antibody at 10microg/ml Lane 1: Mouse brain tissue Lane 2: A549 whole cell lysate Lane 3: MCF-7 whole cell lysate Lane 4: A375 whole cell lysate Lane 5: U251 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 96, 94 kDa Observed band size: 96 kDa
Western blot All lanes: USP5 antibody at 10microg/ml Lane 1: Mouse brain tissue Lane 2: A549 whole cell lysate Lane 3: MCF-7 whole cell lysate Lane 4: A375 whole cell lysate Lane 5: U251 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 96, 94 kDa Observed band size: 96 kDa
USP5 Antibody
CSB-PA025742LA01HU
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetUSP5
Overview
- SupplierCusabio
- Product NameUSP5 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID8078
- Target nameUSP5
- Target descriptionubiquitin specific peptidase 5
- Target synonymsdeubiquitinating enzyme 5; isopeptidase T; ISOT; testicular tissue protein Li 218; ubiquitin carboxyl-terminal hydrolase 5; ubiquitin isopeptidase T; ubiquitin specific protease 5 (isopeptidase T); ubiquitin thioesterase 5; ubiquitin thiolesterase 5; ubiquitin-specific protease-5 (ubiquitin isopeptidase T); ubiquitin-specific-processing protease 5
- HostRabbit
- IsotypeIgG
- Protein IDP45974
- Protein NameUbiquitin carboxyl-terminal hydrolase 5
- Scientific DescriptionCleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers. Involved in unanchored \\\Lys-48\\\-linked polyubiquitin disassembly. Binds linear and \\\Lys-63\\\-linked polyubiquitin with a lower affinity. Knock-down of USP5 causes the accumulation of p53/TP53 and an increase in p53/TP53 transcriptional activity because the unanchored polyubiquitin that accumulates is able to compete with ubiquitinated p53/TP53 but not with MDM2 for proteasomal recognition.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203