USP5, Human (sf9, His)
HY-P74479
Protein IDP45974
Product group Proteins / Signaling Molecules
Overview
- SupplierMedChem Express
- Product NameUSP5, Human (sf9, His)
- Delivery Days Customer10
- CertificationResearch Use Only
- Estimated Purity95.20
- Gene ID8078
- Target nameUSP5
- Target descriptionubiquitin specific peptidase 5
- Target synonymsdeubiquitinating enzyme 5; isopeptidase T; ISOT; testicular tissue protein Li 218; ubiquitin carboxyl-terminal hydrolase 5; ubiquitin isopeptidase T; ubiquitin specific protease 5 (isopeptidase T); ubiquitin thioesterase 5; ubiquitin thiolesterase 5; ubiquitin-specific protease-5 (ubiquitin isopeptidase T); ubiquitin-specific-processing protease 5
- Protein IDP45974
- Protein NameUbiquitin carboxyl-terminal hydrolase 5
- Scientific DescriptionUSP5 protein selectively cleaves branched multiubiquitin polymers, favoring Lys-48-linked polyubiquitin disassembly. It exhibits lower affinity for linear and Lys-63-linked polyubiquitin. USP5 knockdown leads to p53/TP53 accumulation, enhancing p53/TP53 transcriptional activity, as unanchored polyubiquitin competes with ubiquitinated p53/TP53 for proteasomal recognition, unlike MDM2. USP5 Protein, Human (sf9, His) is the recombinant human-derived USP5 protein, expressed by Sf9 insect cells , with C-His labeled tag.
- Storage Instruction-20°C
- UNSPSC41116100