USP6 Antibody

Cusabio

USP6 Antibody

20

ImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

USP6

ubiquitin specific peptidase 6

deubiquitinating enzyme 6; HRP1; hyperpolymorphic gene 1; proto-oncogene TRE-2; TBC1D3 and USP32 fusion; TRE17; TRE2; Tre-2; TRESMCR; ubiquitin carboxyl-terminal hydrolase 6; ubiquitin specific peptidase 6 (Tre-2 oncogene); ubiquitin specific protease 6 (Tre-2 oncogene); ubiquitin thioesterase 6; ubiquitin thiolesterase 6; ubiquitin-specific protease USP6; ubiquitin-specific-processing protease 6; USP6-short

Rabbit

IgG

Ubiquitin carboxyl-terminal hydrolase 6

Deubiquitinase with an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. Catalyzes its own deubiquitination. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity. Promotes plasma membrane localization of ARF6 and selectively regulates ARF6-dependent endocytic protein trafficking. Is able to initiate tumorigenesis by inducing the production of matrix metalloproteinases following NF-kappa-B activation.

Human, Rat

-20°C or -80°C

41116161