USP9X Antibody, Biotin conjugated

Cusabio

USP9X Antibody, Biotin conjugated

20

ELISA

Research Use Only

Polyclonal

Biotin

USP9X

ubiquitin specific peptidase 9 X-linked

deubiquitinating enzyme FAF-X; DFFRX; Drosophila fat facets related, X-linked; FAF; FAM; fat facets in mammals; fat facets protein related, X-linked; hFAM; MRX99; MRXS99F; probable ubiquitin carboxyl-terminal hydrolase FAF-X; ubiquitin specific protease 9, X chromosome (fat facets-like Drosophila); ubiquitin thioesterase FAF-X; ubiquitin thiolesterase FAF-X; ubiquitin-specific processing protease FAF-X; ubiquitin-specific protease 9, X chromosome; XLID99

Rabbit

IgG

Probable ubiquitin carboxyl-terminal hydrolase FAF-X

Deubiquitinase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Essential component of TGF-beta/BMP signaling cascade. Regulates chromosome alignment and segregation in mitosis by regulating the localization of BIRC5/survivin to mitotic centromeres. Specifically hydrolyzes both \Lys-29\- and \Lys-33\-linked polyubiquitins chains. Specifically deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33. Involved in axonal growth and neuronal cell migration.

Human

-20°C or -80°C

12352203