UVRAG antibody
GTX135222
Overview
- SupplierGeneTex
- Product NameUVRAG antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.84 mg/ml
- ConjugateUnconjugated
- Gene ID7405
- Target nameUVRAG
- Target descriptionUV radiation resistance associated
- Target synonymsbeclin 1 binding protein; DHTX; disrupted in heterotaxy; p63; UV radiation resistance-associated gene protein; VPS38
- HostRabbit
- IsotypeIgG
- Protein IDQ9P2Y5
- Protein NameUV radiation resistance-associated gene protein
- Scientific DescriptionThis gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer. [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203