Uzarigenin

MedChem Express

Uzarigenin [466-09-1]

14

466-09-1

Research Use Only

C23H34O4

374.51

Uzarigenin (NSC 119993; NSC 277290; Odorigeni) is a carnolide can be isolated from Pergularia tomentosa and exhibits antiproliferative activity. Uzarigenin resists the proliferation of PC3 cells, HeLa cells, Calu-1 cells, MCF-7 cells and U251MG cells, with IC50 values of 0.3 microM, 3.0 microM, 8.0 microM, 6.0 microM and 6.0 microM respectively[1].

O=C1OCC([C@H]2CC[C@]3(O)[C@]4([H])CC[C@@]5([H])C[C@@H](O)CC[C@]5(C)[C@@]4([H])CC[C@]23C)=C1

12352200